This study investigates the biomechanical and clinical effects of the Goshgarian-type Transpalatal Arch (TPA) on inter-molar distances in patients with maxillary dental posterior crossbite. A sample of 100 patients was analyzed to enhance sta Read more

Chondromas are benign cartilaginous tumors most commonly arising in the small bones, while sacral involvement remains exceedingly rare. We report the case of a 53-year-old male patient presenting with pelvic pain. Imaging studies revealed a p Read more

The growing global burden of metabolic diseases alongside recurrent infectious disease outbreaks has exposed fundamental limitations in disease surveillance systems that remain siloed, reactive, and disease specific, despite increasing eviden Read more

Relapse remains a defining challenge in the long-term management of substance use disorders, underscoring the need for approaches that move beyond episodic treatment and retrospective assessment. Our review examines the emerging role of digit Read more

The widespread adoption of universal antiretroviral therapy has transformed the global HIV response and led to substantial reductions in HIV-related mortality. However, advanced HIV disease continues to contribute disproportionately to deaths Read more

Background: The HIV care cascade is widely used to monitor national HIV responses, yet persistent losses across cascade stages continue to undermine epidemic control. Methods: We conducted a structured narrat Read more

Alzheimer’s disease (AD) is a progressive neurodegenerative disorder characterized by cognitive decline, memory loss, and behavioural changes, significantly impacting patients’ quality of life and placing a substantial burden on h Read more

We read with interest the article by Meldau et al. on the frequency of pathogenic mtDNA variants in African L-haplogroups in patients with mitochondrial disorders (MIDs) from an African and a US center [1]. Haplogroup context was determined in 82 Read more

With the global population aging rapidly, the incidence of stroke and its associated burden on healthcare systems and society are projected to rise significantly. Stroke survivors often experience a range of long-term complications, including sens Read more

It is generally accepted that Coxsackievirus B (CVB) infections are a major factor in initiating or hastening the development of type 1 diabetes (T1D) and islet autoimmunity, especially in people with genetic predispositions. These viruses ha Read more